Department of Orthopaedic Surgery

The Department of Orthopaedic Surgery offers services and programs through the following Divisions. Use these links to directly access all our Department sites.

Welcome to the Department of

Orthopaedic Surgery



  • Parnassus Heights
  • 513 Parnassus Avenue
    S-1164, Box 0514
    San Francisco, CA 94143
    Phone: 415-502-3056

Jeffrey Lotz, PhD

Jeffrey Lotz, PhD


Professor Jeffrey Lotz, Ph.D. has been the Director of the Orthopaedic Bioengineering Laboratory at UCSF since 1992. Dr. Lotz earned a doctorate degree in Medical Engineering from the Harvard/MIT Division of Health Sciences and Technology, a Masters Degree in Mechanical Engineering Design from Stanford University, and Bachelors of Science in Mechanical Engineering from UC Berkeley. Prior work experience includes medical device design (Stanford Research Institute) and medical device failure evaluation (Failure Analysis Associates). Dr. Lotz is a Member of the NIH Peer Review Committee for Tissue Engineering Grants.

As a principal investigator, Dr. Lotz has procured over $9M in extramural funding for spine-related projects. He has earned several awards for spine research, including the ISSLS Prize (2007), Volvo Award (1998), and the North American Spine Society Award (1993). He serves as a Deputy Editor for the journal Spine, and an Associate Editor for The Spine Journal. He has expertise in spine biomechanics and intervertebral disc biology and has published 100 peer-reviewed journal articles. His laboratory work focuses on identifying mechanisms of intervertebral disc degeneration, exploring tissue engineering approaches for treating low back pain, and the biomechanics of spinal instrumentation.