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Molecular Biology Lab Research Staff
Director: Ralph Marcucio, PhD, Assistant Professor
Senior Specialist: Celine Colnot, PhD
Senior Specialist: Diane Hu, MD
Diane Hu was born in Sizhuan, China and received her Medical Degree in China in 1985. Dr. Hu joined the Molecular and Cellular Biology Laboratory in the Department of Orthopaedic Surgery at the University of California at San Francisco upon her arrival in the U.S. in 1994. She became a U.S. citizen in the millennium year 2000.
The investigation of signaling pathways that mediate craniofacial morphogenesis by examining how perturbations to these pathways result in craniofacial malformations and contributions to studies that examine fracture repair have garnered Dr. Hu co-authorship in more then 10 manuscripts published in internationally recognized journals.
Dr. Hu is both an accomplished scientist and lab manager, and she has been vital to the establishment of the molecular biology research program at SFGH. In her role as lab manager, she is responsible for training postdoctoral fellows, students, residents, and laboratory technicians in a variety of scientific methodologies including: standard molecular biological techniques, tissue culture, immuno-histochemistry, and microsurgery on small animals.
Senior Specialist: Chuanyong Lu
Chuanyong Lu was born and grew up in China. Chuanyong Lu graduated from Beijing Medical University with a Bachelor's Degree in 1994. He began his residency training in orthopaedic surgery in 1994, and in 1997, Dr. Lu matriculated at the Medical School of Peking University. In 2000, Dr. Lu received an award given to one of the top medical students at Peking University. Upon completion of his residency training in 2000, Dr. Lu became a member of the faculty of the Department of Orthopaedic Surgery at Peking University.
In addition to his clinical responsibilities, Dr. Lu carried out clinical research on osteoporosis and basic research on osteo-integration of joint prostheses during his residency training. This work resulted in several publications. In 2001, Dr. Lu joined the Molecular and Cellular Biology Research Laboratory in the Department of Orthopaedic Surgery at the University of California, San Francisco. He has received extensive training in the histological and molecular analyses of skeletal development and regeneration. In addition, he completed several projects, including the effect of mechanical stimuli on stem cell differentiation during fracture healing and the use of biomaterials to enhance bone regeneration. His current research focuses on the molecular regulation of fracture healing, including the effect of aging on healing and the role of angiogenesis during repair.
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