Department of Orthopaedic Surgery

The Department of Orthopaedic Surgery offers services and programs through the following Divisions. Use these links to directly access all our Department sites.

Research

Current Clinical Trials

 

Multicenter Retrospective Outcome Assessment of Open Reduction Internal Fixation (ORIF) vs. Closed Reduction Internal Fixation (CRIF) in Treatment of Adults with Femoral Neck Fractures (Femoral Neck Fracture Study)

The purpose of this study is to compare the rate of reoperation following the initial ORIF versus CRIF of displaced femoral neck fractures in adults as the primary outcome.

 

Optimal Grafting Options for Large Bone Defects of the Tibia (pTOG)

The purpose of this METRC study is to determine if rhBMP-2, a bone graft substitute, is as effective as using bone from the hip (iliac crest autograft) to help promote healing of open, tibia fractures with a bone defect. Read more about the pTOG study here.

 

Optimal Fixation of Open Tibia Fractures (FIXIT)

This METRC study will compare two standard options for treating severe open tibia fractures: internal fixation with a nail or plate and external ring fixation. Read more about the FIXIT study here.

 

Oral Versus Intravenus Therapy for Surgical Site Infections Following Fracture Treatment (POvIV)

The goal of this study is to investigate the efficacy of oral (par oris – PO) antibiotic therapy versus intravenous (IV) systemic antibiotics in the treatment of acute infection after plate fixation of fractures. Read more about the POvIV study here.

 

Plate Versus Intramedullary Nail Fixation of Proximal Tibia Fractures (IMPRESS)

The two most common methods of fixation for proximal tibia fractures are intramedullary nailing and plate fixation. The purpose of this study is to compare the outcomes of these two techniques.

 

Evaluation of Tibial Plateau Fractures with Quantitative MRI

Post-traumatic osteoarthritis (PTOA) is a disabling condition affecting patients with articular trauma.  Several agents now show promise in mitigating the effect of joint injuries and preventing PTOA, but study in humans is limited by the variable latency of the condition and availability of a valid outcome measurement.  Recently described magnetic resonance (MR) imaging techniques can quantitatively assess morphology and biochemical changes in cartilage and bone in osteoarthritis of the knee. We are trying to validate MR imaging techniques as a surrogate for joint health and early PTOA after operative treatment of high-energy tibial plateau fracture. 

DoseAware Study

This study will assess real-time radiation exposure from c-arm fluoroscopy during selected orthopaedic trauma surgeries of the ankle, wrist, hip and tibial plateau.   Real-time dosimetry devices, such as DoseAware, may limit radiation exposure during orthopaedic trauma cases that require fluoroscopy.