Surgical Site Infection Rate and Assessment of Risk Factors Among Orthopaedic Patients at a Level I Urban Trauma Center Following Fracture Fixation
The goal of this project is to determine the incidence of Surgical Site Infection of orthopaedic patients having undergone surgical treatment of fractures in an urban hospital setting also to ascertain what the potential risk factors are among this unique study population.
The Relative Effect of Cephalomedullary Nails Versus Sliding Hip Screw in the Treatment of Intertrochanteric Hip Fractures on Mortality and Re-operation: A Comparative Retrospective Cohort Study
This study is a collaborative effort between University of California San Francisco and Kaiser Permanente involving a large cohort comparing consecutive series of IMHSs and DHSs virtually exclusively used over the same period at different Kaiser institutions. The project focuses on the relative performance of cephalomedullary nails (Intrmedullary Hip Screw and Gamma Nail) versus sliding hip screw (Dynamic Hip Screw and AMBI) in the treatment of intertrochanteric hip fractures as measured by need for revision surgery and mortality at 2 years follow-up.
Incidence of Genetic Polymorphisms that may Influence Bone Healing in the Hospital and General Population
During the past century great advances were made in the management of fractures. In addition to the evolution of better orthopaedic implants, the role of biological fixation became very popular. The concept of biological osteosynthesis refers basically to the conservation of the vascularity of the bone during surgical intervention to ensure the continued vitality of the individual fragments and to achieve improved fracture healing. The goal of this study is to determine whether genetic polymorphisms exist that increases the risk of developing nonunion fractures.
Definitive fixation of long bone fractures in poly trauma patients with hypoperfusion
This study will test whether definitive fixation of lower-extremity long bone fractures in poly trauma patients in the setting of hypoperfusion leads to higher rates of multi-organ failure compared to those who were adequately resuscitated.